Progesterone Receptor Antikörper (N-Term)
-
- Target Alle Progesterone Receptor (PGR) Antikörper anzeigen
- Progesterone Receptor (PGR)
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Progesterone Receptor Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- TELKAKGPRA PHVAGGPPSP EVGSPLLCRP AAGPFPGSQT SDTLPEVSAI
- Homologie
- Human: 100%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PGR. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PGR
- Top Product
- Discover our top product PGR Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 933 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Progesterone Receptor (PGR)
- Andere Bezeichnung
- PGR (PGR Produkte)
- Synonyme
- NR3C3 antikoerper, PR antikoerper, 9930019P03Rik antikoerper, BB114106 antikoerper, ENSMUSG00000074510 antikoerper, PR-A antikoerper, PR-B antikoerper, XPR-1 antikoerper, pgr antikoerper, xpr-2 antikoerper, LOC443444 antikoerper, PGR antikoerper, pg antikoerper, pr antikoerper, gb:dq017620 antikoerper, progesterone receptor antikoerper, progesterone receptor L homeolog antikoerper, PGR antikoerper, Pgr antikoerper, pgr.L antikoerper, pgr antikoerper
- Hintergrund
-
This protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NR3C3, PR
Protein Interaction Partner: BCAS2, SRC, PGR, Dlg4, PARP1, ANP32A, XRCC5, PRKDC, XRCC6, MAGEA11, FKBP5, RBM23, RBM39, KAT2B, BRCA1, STUB1, DNAJC7, PPP5C, FKBP4, BPTF, CDK2, COPS5, NCOA1, UBC, ESR1, NCOA2, CCNA1, NCOA3, STAT3, SP1, Jdp2, Batf3, STAT5B, STAT5A, FGFR2, PRDM2, NCOR2, TAF
Protein Size: 933 - Molekulargewicht
- 99 kDa
- Gen-ID
- 5241
- NCBI Accession
- NM_000926, NP_000917
- UniProt
- P06401
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
-