TWIST1 Antikörper (C-Term)

Produktnummer ABIN2780347

Der Kaninchen Polyklonal Anti-TWIST1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, TWIST1 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Schwein, Hund, Kaninchen und Meerschweinchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für TWIST1 Antikörper (C-Term) (ABIN2780347)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Schwein, Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWIST1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TWIST1 Antikörper

Bindungsspezifität: C-Term

Sequenz: DKLSKIQTLK LAARYIDFLY QVLQSDELDS KMASCSYVAH ERLSYAFSVW

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TWIST1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TWIST1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 202 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TWIST1 Antikörper (ABIN2780347)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Details zu TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Andere Bezeichnung: TWIST1

Hintergrund: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation.TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
Alias Symbols: SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38
Protein Interaction Partner: UBC, HOXA5, ETS2, TP53, KAT2B, SETD8, HES6, MTA2, BRAP, TCF3, RELA, PPP2CA, HDAC2, CHD3, TWIST2, ELSPBP1, WDR5, HDAC3, RBBP7, CHD4, SOX2, EP300, TWIST1, GLI3, MYOD1,
Protein Size: 202

Molekulargewicht: 21 kDa

Gen-ID: 7291

NCBI Accession: NM_000474, NP_000465

UniProt: Q15672

Pathways: p53 Signalweg, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity