MITF Antikörper (N-Term)

Produktnummer ABIN2780333

Dieser Anti-MITF-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von MITF in WB. Geeignet für Human, Maus, Hund, Ratte, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Zebrafisch (Danio rerio) und Ziege.

Kurzübersicht für MITF Antikörper (N-Term) (ABIN2780333)

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reaktivität: Human, Maus, Hund, Ratte, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MITF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MITF Antikörper

Bindungsspezifität: N-Term

Sequenz: THLENPTKYH IQQAQRQQVK QYLSTTLANK HANQVLSLPC PNQPGDHVMP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MITF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MITF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 419 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MITF

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Andere Bezeichnung: MITF

Hintergrund: MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MI, WS2, WS2A, bHLHe32
Protein Interaction Partner: EBP, STUB1, HK3, EPAS1, LEF1, APP, HINT1, ELAVL1, CDK2, SUMO2, PSMD14, MARK3, PIAS3, PIAS2, PIAS1, SUMO1, UBE2I, PAX3, OTX2, PAX6, PATZ1, GSK3B, TFEC, EP300, RPS6KA1, TFEB, MAPK14, TFE3, MAPK1, SPI1, FOS, CTNNB1, CDKN1A, RB1,
Protein Size: 419

Molekulargewicht: 47 kDa

Gen-ID: 4286

NCBI Accession: NM_000248, NP_000239

Pathways: Chromatin Binding