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G3BP1 Antikörper (N-Term)

G3BP1 Reaktivität: Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Rind (Kuh), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780221
  • Target Alle G3BP1 Antikörper anzeigen
    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
    Bindungsspezifität
    • 21
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 75
    • 25
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Rind (Kuh), Schwein
    Wirt
    • 69
    • 5
    • 1
    Kaninchen
    Klonalität
    • 69
    • 6
    Polyklonal
    Konjugat
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser G3BP1 Antikörper ist unkonjugiert
    Applikation
    • 68
    • 32
    • 29
    • 18
    • 13
    • 13
    • 11
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EVFGGFVTEP QEESEEEVEE PEERQQTPEV VPDDSGTFYD QAVVSNDMEE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against G3BP. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human G3BP
    Top Product
    Discover our top product G3BP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 466 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lind, Svedin, Domsgen, Kapell, Laitinen, Moll, Flodström-Tullberg: "Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).

    Schulte, Liu, Panas, Thaa, Dickson, Götte, Achour, McInerney: "Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication." in: Open biology, Vol. 6, Issue 7, (2016) (PubMed).

  • Target
    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
    Andere Bezeichnung
    G3BP (G3BP1 Produkte)
    Synonyme
    G3BP antikoerper, HDH-VIII antikoerper, fj17h05 antikoerper, zgc:56034 antikoerper, wu:fj17h05 antikoerper, g3bp antikoerper, MGC53271 antikoerper, G3BP1 antikoerper, G3bp antikoerper, RGD1310666 antikoerper, AI849976 antikoerper, B430204O07 antikoerper, C87777 antikoerper, mKIAA4115 antikoerper, G3BP stress granule assembly factor 1 antikoerper, GTPase activating protein (SH3 domain) binding protein 1 antikoerper, GTPase activating protein (SH3 domain) binding protein 1 L homeolog antikoerper, Ras-GTPase-activating protein SH3-domain-binding protein antikoerper, G3BP1 antikoerper, g3bp1 antikoerper, g3bp1.L antikoerper, LOC100304885 antikoerper, G3bp1 antikoerper
    Hintergrund
    G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: G3BP, HDH-VIII
    Protein Interaction Partner: UBC, USP10, FXR2, MDM2, RNF2, BMI1, RPS27L, EDC4, RPL35, RPL14, EIF2B3, EIF3C, PTBP1, PIN1, PA2G4, YBX1, HNRNPU, FAU, SH3RF2, TARDBP, FBXO25, RIOK2, SND1, VCAM1, env, ITGA4, IL7R, FN1, EPHA8, DTX1, PABPC1, PAXIP1, ESR1, APP, NOLC1, TPM4, LCK, CSK, KCND3,
    Protein Size: 466
    Molekulargewicht
    51 kDa
    Gen-ID
    10146
    NCBI Accession
    NM_005754, NP_005745
    UniProt
    Q13283
    Pathways
    SARS-CoV-2 Protein Interaktom
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