Glutamate Receptor 1 Antikörper (N-Term)

Produktnummer ABIN2780202

Der Kaninchen Polyklonal anti-Glutamate Receptor 1 Antikörper wird verwendet zum Nachweis von Glutamate Receptor 1 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für Glutamate Receptor 1 Antikörper (N-Term) (ABIN2780202)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Gria1 Antibody - N-terminal region

Sequenz: CGALHVCFIT PSFPVDTSNQ FVLQLRPELQ EALISIIDHY KWQTFVYIYD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against Gria1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37670-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: Gria1

Hintergrund:

Background Information: Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene Name: Glutamate receptor, ionotropic, AMPA1 (alpha 1)

Alternative Symbols: Gl, HI, Glr, Glu, Glr1, Glur, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, gluR-K1, 2900051M01Rik

Protein Name: Glutamate receptor 1

Molekulargewicht: 102kDa

Gen-ID: 14799

NCBI Accession: NP_001106796

UniProt: P23818

Pathways: PI3K-Akt Signalweg