Glypican 3 Antikörper (Middle Region)
Kurzübersicht für Glypican 3 Antikörper (Middle Region) (ABIN2780199)
Target
Alle Glypican 3 (GPC3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- FSTIHDSIQY VQKNAGKLTT TIGKLCAHSQ QRQYRSAYYP EDLFIDKKVL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GPC3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GPC3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 580 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).
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Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).
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- Glypican 3 (GPC3)
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Andere Bezeichnung
- GPC3
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Hintergrund
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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
Alias Symbols: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
Protein Interaction Partner: UBC, WNT3A, WNT7B, IGF2, FGF2,
Protein Size: 580 -
Molekulargewicht
- 64 kDa
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Gen-ID
- 2719
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NCBI Accession
- NM_004484, NP_004475
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UniProt
- P51654
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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