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Glypican 3 Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-Glypican 3-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Glypican 3 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2780199

Kurzübersicht für Glypican 3 Antikörper (Middle Region) (ABIN2780199)

Target

Alle Glypican 3 (GPC3) Antikörper anzeigen
Glypican 3 (GPC3)

Reaktivität

  • 169
  • 50
  • 49
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt

  • 99
  • 69
  • 5
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 92
  • 77
  • 5
Polyklonal

Konjugat

  • 85
  • 14
  • 7
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glypican 3 Antikörper ist unkonjugiert

Applikation

  • 93
  • 85
  • 80
  • 58
  • 53
  • 30
  • 26
  • 18
  • 15
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 20
    • 16
    • 12
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    FSTIHDSIQY VQKNAGKLTT TIGKLCAHSQ QRQYRSAYYP EDLFIDKKVL

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against GPC3. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human GPC3
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 580 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bhave, Mars, Donthamsetty, Zhang, Tan, Luo, Bowen, Michalopoulos: "Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).

  • Target

    Glypican 3 (GPC3)

    Andere Bezeichnung

    GPC3

    Hintergrund

    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
    Alias Symbols: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
    Protein Interaction Partner: UBC, WNT3A, WNT7B, IGF2, FGF2,
    Protein Size: 580

    Molekulargewicht

    64 kDa

    Gen-ID

    2719

    NCBI Accession

    NM_004484, NP_004475

    UniProt

    P51654

    Pathways

    Glycosaminoglycan Metabolic Process
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