ECSIT Antikörper (N-Term)
Kurzübersicht für ECSIT Antikörper (N-Term) (ABIN2779983)
Target
Alle ECSIT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- EPWLVPRPPE PQRKPIKVPA MHEDSFKPSG NRERDKASFL NAVRSFGAHN
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Homologie
- Mouse: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Ecsit. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Antigen size: 435 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ECSIT
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Andere Bezeichnung
- Ecsit
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Hintergrund
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Ecsit is required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Ecsit is an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1.Ecsit promotes proteolytic activation of MAP3K1. Ecsit is involved in the BMP signaling pathway. Ecsit is required for normal embryonic development.
Alias Symbols: Sitpec
Protein Interaction Partner: Map3k1, Traf6, Irak1, SMURF1,
Protein Size: 435 -
Molekulargewicht
- 50 kDa
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Gen-ID
- 26940
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NCBI Accession
- NM_012029, NP_036159
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UniProt
- Q9QZH6
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Pathways
- TLR Signalweg, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom
Target
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