TFAM Antikörper (C-Term)

Produktnummer ABIN2779903

Der Kaninchen Polyklonal anti-TFAM Antikörper (ABIN2779903) detektiert spezifisch TFAM in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Ratte, Rind (Kuh) und Kaninchen.

Kurzübersicht für TFAM Antikörper (C-Term) (ABIN2779903)

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reaktivität: Maus, Ratte, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TFAM Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Tfam Antibody - C-terminal region

Sequenz: FQEAKDDSAQ GKLKLVNEAW KNLSPEEKQA YIQLAKDDRI RYDNEMKSWE

Homologie: Cow: 79%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Tfam. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse Tfam

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114138

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Andere Bezeichnung: Tfam

Hintergrund:

Background Information: TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.

Gene Name: Transcription factor A, mitochondrial

Alternative Symbols: Hmgt, mtTF, tsHM, Hmgts, mtTFA, tsHMG, AI661103

Protein Name: Transcription factor A, mitochondrial

Molekulargewicht: 29 kDa

Gen-ID: 21780

NCBI Accession: NP_033386

UniProt: P40630

Pathways: Chromatin Binding