TFAM Antikörper (C-Term)

Produktnummer ABIN2779903

Dieses Anti-TFAM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TFAM in WB und IHC. Geeignet für Maus, Ratte, Kaninchen und Rind (Kuh).

Kurzübersicht für TFAM Antikörper (C-Term) (ABIN2779903)

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reaktivität: Maus, Ratte, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TFAM Antikörper

Bindungsspezifität: C-Term

Sequenz: FQEAKDDSAQ GKLKLVNEAW KNLSPEEKQA YIQLAKDDRI RYDNEMKSWE

Homologie: Cow: 79%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Tfam. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse Tfam

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 243 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Andere Bezeichnung: Tfam

Hintergrund: TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: AI661103, Hmgts, mtTFA, tsHMG
Protein Interaction Partner: C1QBP, SNCA,
Protein Size: 243

Molekulargewicht: 27 kDa

Gen-ID: 21780

NCBI Accession: NM_009360, NP_033386

UniProt: P40630

Pathways: Chromatin Binding