TFAM Antikörper (Middle Region)
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- Target Alle TFAM Antikörper anzeigen
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Maus, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TFAM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SESFQEAKDD SAQGKLKLVN EAWKNLSPEE KQAYIQLAKD DRIRYDNEMK
- Homologie
- Mouse: 100%, Rabbit: 77%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TFAM. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM
- Top Product
- Discover our top product TFAM Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 243 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Andere Bezeichnung
- TFAM (TFAM Produkte)
- Hintergrund
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Interaction Partner: C1QBP, SNCA,
Protein Size: 243 - Molekulargewicht
- 27 kDa
- Gen-ID
- 21780
- NCBI Accession
- NM_009360, NP_033386
- UniProt
- P40630
- Pathways
- Chromatin Binding
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