NK2 Homeobox 5 Antikörper (N-Term)
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- Target Alle NK2 Homeobox 5 (NKX2-5) Antikörper anzeigen
- NK2 Homeobox 5 (NKX2-5)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MFPSPALTPT PFSVKDILNL EQQQRSLASG DLSARLEATL APASCMLAAF
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 80%, Mouse: 100%, Rabbit: 86%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Nkx2-5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the n terminal region of mouse Nkx2-5
- Top Product
- Discover our top product NKX2-5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 318 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NK2 Homeobox 5 (NKX2-5)
- Andere Bezeichnung
- Nkx2-5 (NKX2-5 Produkte)
- Synonyme
- CHNG5 antikoerper, CSX antikoerper, CSX1 antikoerper, HLHS2 antikoerper, NKX2.5 antikoerper, NKX2E antikoerper, NKX4-1 antikoerper, VSD3 antikoerper, Csx antikoerper, Nkx-2.5 antikoerper, Nkx2.5 antikoerper, tinman antikoerper, nk2.5 antikoerper, nkx2-5 antikoerper, zgc:111912 antikoerper, AR2 antikoerper, XNkx2-5 antikoerper, csx antikoerper, nkx-2.5 antikoerper, nkx2-5b antikoerper, nkx2.5 antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, csx1 antikoerper, nkx2e antikoerper, XNkx-2.5 antikoerper, CNKX-2.5 antikoerper, NKX-2.5 antikoerper, NK2 homeobox 5 antikoerper, NK2 homeobox 5 S homeolog antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, nkx2.5 antikoerper, nkx2-5.S antikoerper, nkx2-5 antikoerper
- Hintergrund
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Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.
Alias Symbols: Csx, Nkx-2.5, Nkx2.5, tinman
Protein Interaction Partner: Tbx5, Foxh1, Hand2, Hand1, Mef2c, Tbx1, Prox1, Smarca4, SRF,
Protein Size: 318 - Molekulargewicht
- 34 kDa
- Gen-ID
- 18091
- NCBI Accession
- NM_008700, NP_032726
- UniProt
- P42582
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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