IRF1 Antikörper (C-Term)

Produktnummer ABIN2779860

Produktdetails anti-IRF1 Antikörper

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HIDGKGYLLN EPGTQLSSVY GDFSCKEEPE IDSPRGDIGI GIQHVFTEMK

Homologie: Cow: 90%, Dog: 80%, Guinea Pig: 86%, Human: 93%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Sheep: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against Irf1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 329 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Andere Bezeichnung: Irf1 (IRF1 Produkte)

Synonyme: irf1 antikoerper, zgc:136945 antikoerper, IRF1 antikoerper, irf11 antikoerper, zgc:103566 antikoerper, IRF-1 antikoerper, MAR antikoerper, AU020929 antikoerper, Irf-1 antikoerper, interferon regulatory factor 1 antikoerper, interferon regulatory factor 1a antikoerper, interferon regulatory factor 1b antikoerper, IRF1 antikoerper, irf1a antikoerper, irf1b antikoerper, Irf1 antikoerper

Hintergrund: Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Irf1 acts as a tumor suppressor.
Alias Symbols: AU020929, Irf-1
Protein Interaction Partner: Ubc, Sumo1, Ube2i, Pias3, Tbk1, Polr2a,
Protein Size: 329

Molekulargewicht: 37 kDa

Gen-ID: 16362

NCBI Accession: NM_008390, NP_032416

UniProt: P15314

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagie