HSF4 Antikörper (Middle Region)

Produktnummer ABIN2779779

Der Kaninchen Polyklonal Anti-HSF4-Antikörper wurde für WB validiert. Er ist geeignet, HSF4 in Proben von Human und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für HSF4 Antikörper (Middle Region) (ABIN2779779)

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HSF4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VTLRQSHGQQ HRVIGKLIQC LFGPLQAGPS NAGGKRKLSL MLDEGSSCPT

Homologie: Human: 100%, Rabbit: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against HSF4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSF4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 463 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HSF4 Antikörper (ABIN2779779)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu HSF4

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Andere Bezeichnung: HSF4

Hintergrund: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Alias Symbols: CTM
Protein Interaction Partner: SESTD1, MYO15A, TIMM13, SUGT1, RABEP1, TARBP1, HSF2, HSF1, FKBP5, DUSP26, MAPK1, SUMO1, ZBED8, NUDT21, CDK2AP2, BCL6, SMARCA4, SLC27A5, HSF4, MAPK3, MAPK8, MAPK14,
Protein Size: 463

Molekulargewicht: 50 kDa

Gen-ID: 3299

NCBI Accession: NM_001538, NP_001529

Pathways: MAPK Signalweg