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SIRT4 Antikörper (N-Term)

SIRT4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen, Schaf, Meerschweinchen, Ziege, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779655
  • Target Alle SIRT4 Antikörper anzeigen
    SIRT4 (Sirtuin 4 (SIRT4))
    Bindungsspezifität
    • 12
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 50
    • 34
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen, Schaf, Meerschweinchen, Ziege, Zebrafisch (Danio rerio)
    Wirt
    • 50
    • 8
    • 2
    • 1
    Kaninchen
    Klonalität
    • 55
    • 6
    Polyklonal
    Konjugat
    • 30
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIRT4 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 27
    • 15
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    ASPPLDPEKV KELQRFITLS KRLLVMTGAG ISTESGIPDY RSEKVGLYAR
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SIRT4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT4
    Top Product
    Discover our top product SIRT4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 314 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SIRT4 (Sirtuin 4 (SIRT4))
    Andere Bezeichnung
    SIRT4 (SIRT4 Produkte)
    Synonyme
    SIRT4 antikoerper, im:7139453 antikoerper, SIR2L4 antikoerper, 4930596O17Rik antikoerper, sirtuin 4 antikoerper, SIRT4 antikoerper, sirt4 antikoerper, Sirt4 antikoerper
    Hintergrund
    SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
    Alias Symbols: MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4
    Protein Interaction Partner: SKP2, Glud1, UBC, SIRT3, IDE, SLC25A6, SLC25A5,
    Protein Size: 314
    Molekulargewicht
    35 kDa
    Gen-ID
    23409
    NCBI Accession
    NM_012240, NP_036372
    UniProt
    Q9Y6E7
    Pathways
    Negative Regulation of Hormone Secretion
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