SIRT2 Antikörper (C-Term)

Produktnummer ABIN2779606

Der Kaninchen Polyklonal anti-SIRT2 Antikörper (ABIN2779606) detektiert spezifisch SIRT2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Kaninchen, Meerschweinchen, Hund, Rind (Kuh) und Zebrafisch (Danio rerio).

Kurzübersicht für SIRT2 Antikörper (C-Term) (ABIN2779606)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Hund, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIRT2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SIRT2 Antibody - C-terminal region

Sequenz: DVAWLGECDQ GCLALAELLG WKKELEDLVR REHASIDAQS GAGVPNPSTS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against SIRT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111800

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Andere Bezeichnung: SIRT2

Hintergrund:

Background Information: SIRT2 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT2 is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.

Gene Name: Sirtuin 2

Alternative Symbols: SIR2, SIR2L, SIR2L2

Protein Name: NAD-dependent protein deacetylase sirtuin-2

Molekulargewicht: 40kDa

Gen-ID: 22933

NCBI Accession: NP_085096

UniProt: Q8IXJ6