TLE4 Antikörper (N-Term)

Produktnummer ABIN486927

Dieser Anti-TLE4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TLE4 in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für TLE4 Antikörper (N-Term) (ABIN486927)

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TLE4 Antikörper

Bindungsspezifität: N-Term

Sequenz: GAEKHRNSAD YSSESKKQKT EEKEIAARYD SDGEKSDDNL VVDVSNEDPS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TLE4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 773 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Andere Bezeichnung: TLE4

Hintergrund: TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: BCE-1, E(spI), ESG, ESG4, GRG4, BCE1
Protein Interaction Partner: SRPK2, POU2F2, UBC, LIG4, BRCA1, WDR77, PRMT5, PPM1B, CUX1, OTX1, OTX2, TLE4, PAX5, POU2F1, MSX1, HDAC1,
Protein Size: 773

Molekulargewicht: 84 kDa

Gen-ID: 7091

NCBI Accession: NM_007005, NP_008936

UniProt: Q04727

Pathways: WNT Signalweg