TLE4 Antikörper (N-Term)

Produktnummer ABIN2779602

Dieses Anti-TLE4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLE4 in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für TLE4 Antikörper (N-Term) (ABIN2779602)

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TLE4 Antikörper

Bindungsspezifität: N-Term

Sequenz: GAEKHRNSAD YSSESKKQKT EEKEIAARYD SDGEKSDDNL VVDVSNEDPS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TLE4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 773 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Andere Bezeichnung: TLE4

Hintergrund: TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: BCE-1, E(spI), ESG, ESG4, GRG4, BCE1
Protein Interaction Partner: SRPK2, POU2F2, UBC, LIG4, BRCA1, WDR77, PRMT5, PPM1B, CUX1, OTX1, OTX2, TLE4, PAX5, POU2F1, MSX1, HDAC1,
Protein Size: 773

Molekulargewicht: 84 kDa

Gen-ID: 7091

NCBI Accession: NM_007005, NP_008936

UniProt: Q04727

Pathways: WNT Signalweg