T-Box 19 Antikörper (Middle Region)

Produktnummer ABIN2779591

Der Kaninchen Polyklonal anti-T-Box 19 Antikörper wird verwendet zum Nachweis von T-Box 19 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für T-Box 19 Antikörper (Middle Region) (ABIN2779591)

Target: T-Box 19 (TBX19)

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Box 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-T-Box 19 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TBX19 Antibody - middle region

Sequenz: IKYNPFAKAF LDAKERNHLR DVPEAISESQ HVTYSHLGGW IFSNPDGVCT

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against TBX19. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX19

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32364-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu T-Box 19

Target: T-Box 19 (TBX19)

Andere Bezeichnung: TBX19

Hintergrund:

Background Information: TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: T-box 19

Alternative Symbols: TPIT, TBS19, dJ747L4.1

Protein Name: T-box transcription factor TBX19

Molekulargewicht: 48kDa

Gen-ID: 9095

NCBI Accession: NP_005140

UniProt: O60806