Rekombinanter T-Box 19 Antikörper (AA 235-435)

Produktnummer ABIN7859603

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch T-Box 19 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter T-Box 19 Antikörper (AA 235-435) (ABIN7859603)

Target: T-Box 19 (TBX19)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser T-Box 19 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: TBXT-7853R

Produktdetails anti-T-Box 19 Antikörper

Bindungsspezifität: AA 235-435

Verwendungszweck: Recombinant TBXT / T-box transcription factor T / Brachyury Antibody

Spezifität: The T-box gene family consists of members that share a unique DNA binding domain. The best characterized T-box (Tbx) gene, brachyury or T, encodes a transcription factor that plays an important role in early vertebrate development. Tbx genes are a family of developmental regulators with more than 20 members recently identified among invertebrates and vertebrates. Mutations in Tbx genes have been found to cause several human diseases. The understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/brachyury protein, which is a transcription activator. The T-domain is a highly conserved DNA-binding motif originally defined in brachyury and characteristic of the Tbx family of transcription factors. The murine brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in notochord differentiation and posterior mesoderm formation, but develop anterior mesoderm.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 235-435) of human TBXT protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu T-Box 19

Target: T-Box 19 (TBX19)

Andere Bezeichnung: TBXT

Hintergrund:

BRAC_HUMAN, Brachyury homolog, Brachyury protein, Bry, MGC104817, Protein T, SAVA, T, T brachyury homolog, T brachyury transcription factor, T Protein, T, brachyury homolog (mouse), TFT, Transcription factor T

Human chordoma tissue.

Molekulargewicht: 47kDa

Gen-ID: 6862, 389457

UniProt: O15178