EYA3 Antikörper (N-Term)
Kurzübersicht für EYA3 Antikörper (N-Term) (ABIN2779570)
Target
Alle EYA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- KMQESGEQTI SQVSNPDVSD QKPETSSLAS NLPMSEEIMT CTDYIPRSSN
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EYA3. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of human EYA3
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EYA3 (Eyes Absent Homolog 3 (EYA3))
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Andere Bezeichnung
- EYA3
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Hintergrund
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This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
Protein Size: 362 -
Molekulargewicht
- 39 kDa
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Gen-ID
- 2140
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NCBI Accession
- NM_001282560, NP_001269489
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UniProt
- Q99504
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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