AES Antikörper (Middle Region)

Produktnummer ABIN2779565

Produktdetails anti-AES Antikörper

Target: AES (Amino-terminal Enhancer of Split (AES))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AES Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HKQAEIVKRL NGICAQVLPY LSQEHQQQVL GAIERAKQVT APELNSIIRQ

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against AES. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AES

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 264 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AES

Target: AES (Amino-terminal Enhancer of Split (AES))

Andere Bezeichnung: AES (AES Produkte)

Synonyme: AES-1 antikoerper, AES-2 antikoerper, ESP1 antikoerper, GRG antikoerper, GRG5 antikoerper, TLE5 antikoerper, AL024115 antikoerper, Esp1 antikoerper, Grg antikoerper, Grg-5 antikoerper, Grg5 antikoerper, Tle5 antikoerper, zgc:64216 antikoerper, aes-1 antikoerper, aes-2 antikoerper, esp1 antikoerper, grg antikoerper, grg5 antikoerper, tle5 antikoerper, xgrg-5 antikoerper, AES antikoerper, amino-terminal enhancer of split antikoerper, amino-terminal enhancer of split S homeolog antikoerper, AES antikoerper, Aes antikoerper, aes antikoerper, aes.S antikoerper

Hintergrund: AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Protein Interaction Partner: MFAP1, MBNL1, SMAD3, LMO2, LMO1, KRT31, DDX6, CRX, BYSL, BCL6, AES, AEN, CARD9, PARVG, LSM2, HOMEZ, MAGOHB, RNF31, VPS37C, C1orf109, OSGIN1, MED4, PRPF31, GORASP2, KANK2, LDOC1, MTUS2, DIP2A, NCDN, BAHD1, IKZF3, U2AF2, RBPMS, FRS3, NEK6, CALCOCO2, ABI2, T
Protein Size: 264

Molekulargewicht: 29 kDa

Gen-ID: 166

NCBI Accession: NM_198969, NP_945320

UniProt: Q14CJ1

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom