TAF11 Antikörper (N-Term)

Produktnummer ABIN2779473

Der Kaninchen Polyklonal Anti-TAF11-Antikörper wurde für WB validiert. Er ist geeignet, TAF11 in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für TAF11 Antikörper (N-Term) (ABIN2779473)

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TAF11 Antikörper

Bindungsspezifität: N-Term

Sequenz: MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE

Homologie: Cow: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TAF11. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 211 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TAF11 Antikörper (ABIN2779473)

Anish, Hossain, Jacobson, Takada: "Characterization of transcription from TATA-less promoters: identification of a new core promoter element XCPE2 and analysis of factor requirements." in: PLoS ONE, Vol. 4, Issue 4, pp. e5103, (2009) (PubMed).

Details zu TAF11

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Andere Bezeichnung: TAF11

Hintergrund: TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.
Alias Symbols: TAF2I, PRO2134, TAFII28, MGC:15243
Protein Interaction Partner: APPBP2, MED26, HIST3H3, APP, TBP, ELAVL1, POLR2A, ACTB, TAF8, VDR, THRA, NFYC, NFYB, NFYA, LZTR1, TAF9, TAF12, TAF10, TAF5, TAF13, TAF6, TAF4, TAF7, TAF2, CPSF1, TRIM24, TAF1, RXRB, RXRA, RELA, TAF15, GTF2F1, GTF2E1, GTF2B,
Protein Size: 211

Molekulargewicht: 23 kDa

Gen-ID: 6882

NCBI Accession: NM_005643, NP_005634

UniProt: Q15544