DVL1 Antikörper (Middle Region)
Kurzübersicht für DVL1 Antikörper (Middle Region) (ABIN2779456)
Target
Alle DVL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- DVL1 Antibody - middle region
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Sequenz
- LKITIANAVI GADVVDWLYT HVEGFKERRE ARKYASSLLK HGFLRHTVNK
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 87%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DVL1. It was validated on Western Blot.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DVL1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32100-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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Andere Bezeichnung
- DVL1
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Hintergrund
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Background Information: DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Gene Name: Dishevelled, dsh homolog 1 (Drosophila)
Alternative Symbols: DVL, DRS2, DVL1L1, DVL1P1
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Molekulargewicht
- 38kDa
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Gen-ID
- 1855
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UniProt
- A6NKG8
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Pathways
- WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development
Target
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