DVL1 Antikörper (Middle Region)

Produktnummer ABIN2779456

Der Kaninchen Polyklonal Anti-DVL1-Antikörper wurde für WB validiert. Er ist geeignet, DVL1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Kaninchen zu detektieren.

Kurzübersicht für DVL1 Antikörper (Middle Region) (ABIN2779456)

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DVL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DVL1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LKITIANAVI GADVVDWLYT HVEGFKERRE ARKYASSLLK HGFLRHTVNK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against DVL1. It was validated on Western Blot.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DVL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DVL1

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Andere Bezeichnung: DVL1

Hintergrund: DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Alias Symbols: DVL, MGC54245, DVL1L1
Protein Interaction Partner: NCK2, TRIM69, NUMA1, HUWE1, UBC, DVL2, WWOX, SIPA1, PSMA3, LRRK2, ITCH, HECW1, NEDD4, ANXA7, SDC4, NKD2, CYLD, SIRT1, CCDC88C, VANGL1, CXXC4, PPM1A, DYNLT1, HDHD2, BRD7, DAAM1, AXIN1, USP13, SMAD3, SMAD7, FRAT1, RAC1, DVL3, SMAD2, DVL1, SMAD4, CSNK1D, CSN
Protein Size: 353

Molekulargewicht: 38 kDa

Gen-ID: 1855

NCBI Accession: NM_004421

UniProt: A6NKG8

Pathways: WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development