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NKX3-1 Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NKX3-1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.
Produktnummer ABIN2779438

Kurzübersicht für NKX3-1 Antikörper (Middle Region) (ABIN2779438)

Target

Alle NKX3-1 Antikörper anzeigen
NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reaktivität

  • 116
  • 19
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt

  • 73
  • 52
  • 1
Kaninchen

Klonalität

  • 76
  • 50
Polyklonal

Konjugat

  • 57
  • 10
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser NKX3-1 Antikörper ist unkonjugiert

Applikation

  • 66
  • 52
  • 50
  • 40
  • 8
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 58
    • 8
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    KRKQLSSELG DLEKHSSLPA LKEEAFSRAS LVSVYNSYPY YPYLYCVGSW

    Homologie

    Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 234 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    NKX3-1 (NK3 Homeobox 1 (NKX3-1))

    Andere Bezeichnung

    NKX3-1

    Hintergrund

    The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BAPX2, NKX3, NKX3.1, NKX3A
    Protein Interaction Partner: STRA13, CHPF, AEN, RABL6, TEX264, STMN3, LMCD1, SPDEF, CKAP4, HNRNPA0, CCT7, HMG20B, FEM1B, HSP90B1, TPT1, RPL37A, RARG, PTMS, PEBP1, ND4, MNAT1, MAN2B1, RPSA, TOP1, WDR77, TOPORS, KAT2B, SP5, SP4, SP3, SP2, SP1, HDAC1, HIPK2, SRF,
    Protein Size: 234

    Molekulargewicht

    26 kDa

    Gen-ID

    4824

    NCBI Accession

    NM_006167, NP_006158

    UniProt

    Q99801

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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