NKX3-1 Antikörper (Middle Region)
Kurzübersicht für NKX3-1 Antikörper (Middle Region) (ABIN2779438)
Target
Alle NKX3-1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- KRKQLSSELG DLEKHSSLPA LKEEAFSRAS LVSVYNSYPY YPYLYCVGSW
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Homologie
- Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 234 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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Andere Bezeichnung
- NKX3-1
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Hintergrund
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The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAPX2, NKX3, NKX3.1, NKX3A
Protein Interaction Partner: STRA13, CHPF, AEN, RABL6, TEX264, STMN3, LMCD1, SPDEF, CKAP4, HNRNPA0, CCT7, HMG20B, FEM1B, HSP90B1, TPT1, RPL37A, RARG, PTMS, PEBP1, ND4, MNAT1, MAN2B1, RPSA, TOP1, WDR77, TOPORS, KAT2B, SP5, SP4, SP3, SP2, SP1, HDAC1, HIPK2, SRF,
Protein Size: 234 -
Molekulargewicht
- 26 kDa
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Gen-ID
- 4824
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NCBI Accession
- NM_006167, NP_006158
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UniProt
- Q99801
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
Target
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