SMAD5 Antikörper (Middle Region)

Produktnummer ABIN2779414

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMAD5 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Zebrafisch (Danio rerio), Schaf, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für SMAD5 Antikörper (Middle Region) (ABIN2779414)

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Schaf, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMAD5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: YPPSPASSTY PNSPASSGPG SPFQLPADTP PPAYMPPDDQ MGQDNSQPMD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SMAD5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMAD5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 465 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMAD5

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Andere Bezeichnung: SMAD5

Hintergrund: SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.
Alias Symbols: DWFC, JV5-1, MADH5
Protein Interaction Partner: UBC, SUMO1, HECW2, HBG2, BCAT1, SOX5, SNRPA, SNRNP70, SFPQ, RYR2, RBM4, PTPN12, PSMD11, NEDD4, SMAD4, SMAD1, ANKRD13A, PPIL4, SOX7, SMURF2, SMURF1, MTMR10, CHMP3, CXXC5, SF3B1, U2AF2, PNKP, WWP1, NAA20, EPN1, SMAD3, SMAD2, PAX6, COPS5, HGS, EP300, ELAVL1,
Protein Size: 465

Molekulargewicht: 51 kDa

Gen-ID: 4090

NCBI Accession: NM_005903, NP_005894

UniProt: Q99717