PDX1 Antikörper (N-Term)
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- Target Alle PDX1 Antikörper anzeigen
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LYMGRQPPPP PPPQFTSSLG SLEQGSPPDI SPYEVPPLAS DDPAGAHLHH
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Pdx1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product PDX1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 284 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Andere Bezeichnung
- Pdx1 (PDX1 Produkte)
- Synonyme
- GSF antikoerper, IDX-1 antikoerper, IPF1 antikoerper, IUF1 antikoerper, MODY4 antikoerper, PDX-1 antikoerper, STF-1 antikoerper, ipf1 antikoerper, PDX1 antikoerper, IPF-1 antikoerper, Ipf1 antikoerper, Mody4 antikoerper, pdx-1 antikoerper, Idx1 antikoerper, Stf1 antikoerper, zgc:100874 antikoerper, XlHbox-8 antikoerper, xlhbox8 antikoerper, pancreatic and duodenal homeobox 1 antikoerper, pancreatic and duodenal homeobox 1 S homeolog antikoerper, PDX1 antikoerper, pdx1 antikoerper, Pdx1 antikoerper, pdx1.S antikoerper
- Hintergrund
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Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
Alias Symbols: IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
Protein Interaction Partner: Pcif1, Meis1, Hdac1, Hdac2, Ins1, Iapp, Spop, Pax4,
Protein Size: 284 - Molekulargewicht
- 31 kDa
- Gen-ID
- 18609
- NCBI Accession
- NM_008814, NP_032840
- UniProt
- P52946
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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