Choline Acetyltransferase Antikörper (C-Term)
Kurzübersicht für Choline Acetyltransferase Antikörper (C-Term) (ABIN2779369)
Target
Alle Choline Acetyltransferase (CHAT) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- SSFHSCKETS SSKFAKAVEE SLIDMRDLCS LLPPTESKPL ATKEKATRPS
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Homologie
- Dog: 100%, Horse: 100%, Human: 100%, Pig: 91%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CHAT. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 630 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Andere Bezeichnung
- CHAT
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Hintergrund
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CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This protein is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Alias Symbols: CMS1A, CMS1A2, CHOACTASE
Protein Interaction Partner: NEDD9, CAMK2A, CAMK2G, PRKCZ, PRKCG, PRKCD, PRKCE, PRKCB, PRKCA,
Protein Size: 630 -
Molekulargewicht
- 70 kDa
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Gen-ID
- 1103
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NCBI Accession
- NM_020984, NP_066264
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UniProt
- A2BDF5
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Pathways
- Skeletal Muscle Fiber Development
Target
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