Amphiregulin Antikörper (Middle Region)

Produktnummer ABIN2779308

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Amphiregulin in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Hund, Pferd, Schwein und Schaf.

Kurzübersicht für Amphiregulin Antikörper (Middle Region) (ABIN2779308)

Target: Amphiregulin (AREG)

Reaktivität: Human, Rind (Kuh), Hund, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amphiregulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Amphiregulin Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: AREG Antibody - middle region

Sequenz: PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR

Homologie: Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Pig: 91%, Sheep: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against AREG. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AREG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30233-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Amphiregulin

Target: Amphiregulin (AREG)

Andere Bezeichnung: AREG

Hintergrund:

Background Information: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.

Gene Name: Amphiregulin

Alternative Symbols: AR, SDGF, AREGB, CRDGF

Protein Name: Amphiregulin

Molekulargewicht: 28kDa

Gen-ID: 374

NCBI Accession: NP_001648

UniProt: P15514

Pathways: RTK Signalweg, EGFR Signaling Pathway