TRF2 Antikörper (C-Term)

Produktnummer ABIN2779306

Der Kaninchen Polyklonal anti-TRF2 Antikörper wird verwendet zum Nachweis von TRF2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für TRF2 Antikörper (C-Term) (ABIN2779306)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRF2 Antikörper

Bindungsspezifität: C-Term

Sequenz: TVEESEWVKA GVQKYGEGNW AAISKNYPFV NRTAVMIKDR WRTMKRLGMN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TERF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TERF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 500 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Andere Bezeichnung: TERF2

Hintergrund: TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TRBF2, TRF2
Protein Interaction Partner: UBC, TERF2IP, TINF2, EP300, SLX4, RPA3, RPA2, RPA1, BMI1, DCLRE1B, BLM, ATM, VCP, NBN, MRE11A, HMGA1, RAD50, TOP3A, HSP90AA1, TEP1, SF3B2, TOP2A, TFAP4, OCM2, NUMA1, NCL, NASP, HMGN2, HMGN1, HMGB1, H2AFX, XRCC6, CTBP1, ASS1, APEX1, ANXA5, DDX39A, HMGN3, D
Protein Size: 500

Molekulargewicht: 55 kDa

Gen-ID: 7014

NCBI Accession: NM_005652, NP_005643

UniProt: Q15554

Pathways: Zellzyklus, Telomere Maintenance