TCF7L1 Antikörper (N-Term)
Kurzübersicht für TCF7L1 Antikörper (N-Term) (ABIN2779272)
Target
Alle TCF7L1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
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anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (N-Term) antibody
TCF7L1 Reaktivität: Human WB, ChIP-seq, ChIP, CUT&RUN Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 35-84) antibodyTCF7L1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (Internal Region) antibodyTCF7L1 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 489-586) antibodyTCF7L1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 80-99) antibodyTCF7L1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 70-98), (N-Term) antibodyTCF7L1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB43616 unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 72-121) antibodyTCF7L1 Reaktivität: Human, Maus, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 561-588), (C-Term) antibodyTCF7L1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 588 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
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Andere Bezeichnung
- TCF7L1
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Hintergrund
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TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Alias Symbols: TCF-3, TCF3
Protein Interaction Partner: UBC, mdfic, Mdfi, DAZAP2, CTNNB1,
Protein Size: 588 -
Molekulargewicht
- 63 kDa
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Gen-ID
- 83439
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NCBI Accession
- NM_031283, NP_112573
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UniProt
- Q9HCS4
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Pathways
- WNT Signalweg, Stem Cell Maintenance
Target
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