NXF3 Antikörper (C-Term)

Produktnummer ABIN2779117

Dieses Anti-NXF3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NXF3 in WB und IHC. Geeignet für Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen und Ratte.

Kurzübersicht für NXF3 Antikörper (C-Term) (ABIN2779117)

Target: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NXF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NXF3 Antikörper

Bindungsspezifität: C-Term

Sequenz: SSFLVDMWYQ TEWMLCFSVN GVFKEVEGQS QGSVLAFTRT FIATPGSSSS

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 79%, Human: 100%, Pig: 92%, Rabbit: 92%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against NXF3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NXF3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 531 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NXF3

Target: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Andere Bezeichnung: NXF3

Hintergrund: NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
Protein Interaction Partner: NXT2, NXT1, SKIL, NXF1, HHV8GK18_gp81, HNRNPUL1, XPO1, NUP214,
Protein Size: 531

Molekulargewicht: 58 kDa

Gen-ID: 56000

NCBI Accession: NM_022052, NP_071335

UniProt: Q9H4D5