CDKN2AIP Antikörper (C-Term)

Produktnummer ABIN2779115

Dieser Anti-CDKN2AIP Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CDKN2AIP in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd.

Kurzübersicht für CDKN2AIP Antikörper (C-Term) (ABIN2779115)

Target: CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN2AIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CDKN2AIP Antikörper

Bindungsspezifität: C-Term

Sequenz: AIEALKATLD VFFVPLKELA DLPQNKSSQE SIVCELRCKS VYLGTGCGKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CARF. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CARF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 580 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDKN2AIP

Target: CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))

Andere Bezeichnung: CARF

Hintergrund: CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
Alias Symbols: CARF
Protein Interaction Partner: UBC, XRN2, RPA3, RPA2, RPA1, WHSC1, VCP, Cdkn2a, MDC1, BRCA1, BARD1, GGH, EPHX1, MDM2, CUL3, SUMO2, RAD21, DHX58, Clp1,
Protein Size: 580

Molekulargewicht: 64 kDa

Gen-ID: 55602

NCBI Accession: NM_017632, NP_060102

UniProt: Q9NXV6