CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.
Alias Symbols: CPSF, YSH1, CPSF73, CPSF-73
Protein Interaction Partner: UBC, SUMO1, WWOX, AICDA, POLR2A, NPM1, TUT1, SYMPK, CSTF2, CPSF2, PAXIP1, MDC1, BARD1, FIP1L1, POLR1E, WDR33, CPSF1, UBD, SIRT7, SMARCAD1, RRAGA, TBP, CDC73, CLP1, PAPOLA, YWHAG,
Protein Size: 684