CPSF3 Antikörper (Cleavage and Polyadenylation Specific Factor 3, 73kDa) (C-Term)

Details for Product anti-CPSF3 Antibody No. ABIN2779100, Anbieter: Anmelden zum Anzeigen
Antigen
  • CPSF3
  • si:dkey-81b15.1
  • wu:fc32f10
  • zgc:101655
  • CPSF-73
  • CPSF73
  • cleavage and polyadenylation specific factor 3
  • cleavage and polyadenylation specificity factor subunit 3
  • cleavage and polyadenylation specific factor 3 L homeolog
  • cleavage and polyadenylation specific factor 3, 73kDa
  • cleavage and polyadenylation specificity factor 3
  • CPSF3
  • cpsf3
  • CpipJ_CPIJ011955
  • CMU_024380
  • PITG_07110
  • cpsf3.L
  • Cpsf3
Epitop
C-Term
10
10
8
7
4
4
3
3
3
2
2
2
2
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
55
17
12
6
5
4
4
4
3
2
2
1
1
1
Wirt
Kaninchen
45
11
Klonalität
Polyklonal
Konjugat
Dieser CPSF3 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
55
25
9
9
8
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CPSF3
Sequenz DDSILSVTVD GKTANLNLET RTVECEEGSE DDESLREMVE LAAQRLYEAL
Homologie Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against CPSF3. It was validated on Western Blot and immunohistochemistry.
Reinigung Protein A purified
Plasmids, Primers & others Plasmide, Primers & weitere CPSF3 products on genomics-online (e.g. as negative or positive controls)
Antigen Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3)
Andere Bezeichnung CPSF3 (CPSF3 Antibody Abstract)
Hintergrund CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.
Alias Symbols: CPSF, YSH1, CPSF73, CPSF-73
Protein Interaction Partner: UBC, SUMO1, WWOX, AICDA, POLR2A, NPM1, TUT1, SYMPK, CSTF2, CPSF2, PAXIP1, MDC1, BARD1, FIP1L1, POLR1E, WDR33, CPSF1, UBD, SIRT7, SMARCAD1, RRAGA, TBP, CDC73, CLP1, PAPOLA, YWHAG,
Protein Size: 684
Molekulargewicht 75 kDa
Gen-ID 51692
NCBI Accession NM_016207, NP_057291
UniProt Q9UKF6
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 684 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (C-Term) antibody (ABIN2779100) WB Suggested Anti-CPSF3 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positi...
Immunohistochemistry (IHC) image for anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (C-Term) antibody (ABIN2779100) Rabbit Anti-CPSF3 Antibody Paraffin Embedded Tissue: Human Liver Cellular Data: Live...
Western Blotting (WB) image for anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (C-Term) antibody (ABIN2779100) WB Suggested Anti-CPSF3
Antibody Titration: 1.25 µg/mL ELISA Titer: 1:62500
Allgemeine Veröffentlichungen Calzado, Sancho, Muñoz: "Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression." in: Journal of virology, Vol. 78, Issue 13, pp. 6846-54, 2004 (PubMed).

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