CPSF3 Antikörper (C-Term)
Kurzübersicht für CPSF3 Antikörper (C-Term) (ABIN2779100)
Target
Alle CPSF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- DDSILSVTVD GKTANLNLET RTVECEEGSE DDESLREMVE LAAQRLYEAL
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CPSF3. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CPSF3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 684 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CPSF3 (Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3))
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Andere Bezeichnung
- CPSF3
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Hintergrund
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CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.
Alias Symbols: CPSF, YSH1, CPSF73, CPSF-73
Protein Interaction Partner: UBC, SUMO1, WWOX, AICDA, POLR2A, NPM1, TUT1, SYMPK, CSTF2, CPSF2, PAXIP1, MDC1, BARD1, FIP1L1, POLR1E, WDR33, CPSF1, UBD, SIRT7, SMARCAD1, RRAGA, TBP, CDC73, CLP1, PAPOLA, YWHAG,
Protein Size: 684 -
Molekulargewicht
- 75 kDa
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Gen-ID
- 51692
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NCBI Accession
- NM_016207, NP_057291
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UniProt
- Q9UKF6
Target
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