HNRNPH3 Antikörper (N-Term)

Produktnummer ABIN2779031

Dieses Anti-HNRNPH3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HNRNPH3 in WB und IHC. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für HNRNPH3 Antikörper (N-Term) (ABIN2779031)

Target: HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HNRNPH3 Antikörper

Bindungsspezifität: N-Term

Sequenz: DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPH3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPH3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 346 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRNPH3 Antikörper (ABIN2779031)

Larriba, Casado-Vela, Pendás-Franco, Peña, García de Herreros, Berciano, Lafarga, Casal, Muñoz: "Novel snail1 target proteins in human colon cancer identified by proteomic analysis." in: PLoS ONE, Vol. 5, Issue 4, pp. e10221, (2010) (PubMed).

Papazov, Daskalov: "Effect of contour shape of nervous system electromagnetic stimulation coils on the induced electrical field distribution." in: Biomedical engineering online, Vol. 1, pp. 1, (2004) (PubMed).

Details zu HNRNPH3

Target: HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Andere Bezeichnung: HNRPH3

Hintergrund: HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Multiple alternative transcript variants seem to be present for this gene and some appear to have intronic regions in the mRNA. Presently, only two transcript variants are fully described.
Alias Symbols: 2H9, HNRPH3
Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, SUMO1, NEDD8, WWOX, ERG, RNF2, EED, rev, PARK2, STK24, HNRNPH3, HNRNPH1, HNRNPF, HNRNPD, HNRNPA1, FN1, DDX5, ITGA4, IL7R, HNRNPU, C17orf85, tat, HCVgp1, HNRNPUL1, HNRNPA0, CHERP, DDX17, VCAM1, RBM4, VCP, PUF60, SF3A3, HNRNPR, HNR
Protein Size: 346

Molekulargewicht: 38 kDa

Gen-ID: 3189

NCBI Accession: NM_012207, NP_036339

UniProt: P31942