GNB2L1 Antikörper (N-Term)
Kurzübersicht für GNB2L1 Antikörper (N-Term) (ABIN2778965)
Target
Alle GNB2L1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GNB2L1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GNB2L1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 317 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
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Andere Bezeichnung
- GNB2L1
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Hintergrund
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GNB2L1 seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. GNB2L1 may be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, GNB2L1 serves as a platform for SRC activation or inactivation. GNB2L1 may play an important role in the developing brain and neuronal differentiation.
Alias Symbols: Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1
Protein Interaction Partner: MKRN2, LARP4B, HUWE1, UBC, SUMO2, HIF1A, STAU1, TARDBP, ADRB2, PRKCB, TRIM45, RNF2, EZH2, BMI1, SUZ12, rev, PTOV1, RPS8, RPS6, RPS5, RPS3A, RPS27L, EIF3K, SYNCRIP, DYNLL1, RPS3, RPSA, EIF3E, DYNC1LI2, RPS9, RPS27, RPS21, RPS20, RPS18, RPS16, RPS13, RPS12,
Protein Size: 317 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 10399
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NCBI Accession
- NM_006098, NP_006089
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UniProt
- P63244
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Pathways
- cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity
Target
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