Nucleolin Antikörper (N-Term)

Produktnummer ABIN2778935

Der Kaninchen Polyklonal Anti-Nucleolin-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Nucleolin in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Pferd, Saccharomyces cerevisiae und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Nucleolin Antikörper (N-Term) (ABIN2778935)

Target: Nucleolin (NCL)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nucleolin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Nucleolin Antikörper

Bindungsspezifität: N-Term

Sequenz: GKALVATPGK KGAAIPAKGA KNGKNAKKED SDEEEDDDSE EDEEDDEDED

Homologie: Cow: 87%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 91%, Pig: 86%, Rabbit: 77%, Rat: 93%, Yeast: 83%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NCL. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 710 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Nucleolin Antikörper (ABIN2778935)

Shefer, Boulos, Gotea, Arafat, Ben Chaim, Muharram, Isaac, Eden, Sperling, Elnitski, Sperling: "A novel role for nucleolin in splice site selection." in: RNA biology, Vol. 19, Issue 1, pp. 333-352, (2022) (PubMed).

Details zu Nucleolin

Target: Nucleolin (NCL)

Andere Bezeichnung: NCL

Hintergrund: Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
Alias Symbols: C23
Protein Interaction Partner: HUWE1, PIK3R1, PA2G4, NCL, HNRNPD, AURKA, MDM2, NFE4, CDKN1A, ADAP1, STAU1, ADAP2, UBC, NUP62, ZBTB1, ARFGEF1, RPA3, RPA2, RPA1, ERG, RNF2, SUZ12, EED, EZH2, BMI1, NPM3, EIF3G, XRCC5, PLOD2, NCBP1, MCM2, LMNA, PRMT1, HNRNPK, KCTD12, DNM1, ACLY, SRPK3, TAR
Protein Size: 710

Molekulargewicht: 78 kDa

Gen-ID: 4691

NCBI Accession: NM_005381, NP_005372

UniProt: P19338

Pathways: Ribonucleoprotein Complex Subunit Organization