EIF4E2 Antikörper (N-Term)
Kurzübersicht für EIF4E2 Antikörper (N-Term) (ABIN2778915)
Target
Alle EIF4E2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- KDDDSGDHDQ NEENSTQKDG EKEKTERDKN QSSSKRKAVV PGPAEHPLQY
-
Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against EIF4E2. It was validated on Western Blot and immunohistochemistry.
-
Aufreinigung
- Protein A purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4E2
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 245 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1." in: FEBS letters, Vol. 564, Issue 1-2, pp. 58-62, (2004) (PubMed).
-
: "Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1." in: FEBS letters, Vol. 564, Issue 1-2, pp. 58-62, (2004) (PubMed).
-
- EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))
-
Andere Bezeichnung
- EIF4E2
-
Hintergrund
-
EIF4E2 belongs to the eukaryotic initiation factor 4E family. It recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Alias Symbols: 4EHP, IF4e, 4E-LP, EIF4EL3
Protein Interaction Partner: USHBP1, CARD9, PRDM14, HOMEZ, TRIM54, NECAB2, ADAMTSL4, AMOTL2, SPAG5, SPRY2, HUWE1, TMCC2, MAGED1, TCF4, TADA2A, TRIM27, REL, MYOG, KRT31, KRT19, KRT13, CDR2, AES, MAPRE3, NOTCH2NL, KRTAP10-8, KRTAP10-5, KRTAP10-9, ZBTB9, SPERT, USP54, MIPOL1, KRT40, UBX
Protein Size: 245 -
Molekulargewicht
- 27 kDa
-
Gen-ID
- 9470
-
NCBI Accession
- NM_004846, NP_004837
-
UniProt
- O60573
-
Pathways
- SARS-CoV-2 Protein Interaktom
Target
-