AIMP1 Antikörper (N-Term)

Produktnummer ABIN2778912

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-AIMP1 Antikörper wird verwendet zum Nachweis von AIMP1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio) und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für AIMP1 Antikörper (N-Term) (ABIN2778912)

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AIMP1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SCYE1 Antibody - N-terminal region

Sequenz: LLKEKAILQA TLREEKKLRV ENAKLKKEIE ELKQELIQAE IQNGVKQIPF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SCYE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SCYE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40551-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AIMP1 Antikörper (ABIN2778912)

Tandle, Mazzanti, Alexander, Roberts, Libutti: "Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells." in: Cytokine, Vol. 30, Issue 6, pp. 347-58, (2005) (PubMed).

Details zu AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Andere Bezeichnung: SCYE1

Hintergrund:

Background Information: SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.

Gene Name: Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Alternative Symbols: p43, HLD3, EMAP2, SCYE1, EMAPII

Protein Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

Molekulargewicht: 34kDa

Gen-ID: 9255

NCBI Accession: NP_004748

UniProt: Q12904