SNRPA1 Antikörper (Middle Region)

Produktnummer ABIN2778901

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-SNRPA1 Antikörper wird verwendet zum Nachweis von SNRPA1 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Zebrafisch (Danio rerio) und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für SNRPA1 Antikörper (Middle Region) (ABIN2778901)

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SNRPA1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SNRPA Antibody - middle region

Sequenz: MPGQMPPAQP LSENPPNHIL FLTNLPEETN ELMLSMLFNQ FPGFKEVRLV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SNRPA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SNRPA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40531-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SNRPA1 Antikörper (ABIN2778901)

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Details zu SNRPA1

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Andere Bezeichnung: SNRPA

Hintergrund:

Background Information: SNRPA binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.

Gene Name: Small nuclear ribonucleoprotein polypeptide A

Alternative Symbols: U1A, Mud1, U1-A

Protein Name: U1 small nuclear ribonucleoprotein A

Molekulargewicht: 31kDa

Gen-ID: 6626

NCBI Accession: NP_004587

UniProt: P09012