SNRPA1 Antikörper (Middle Region)

Produktnummer ABIN2778901

Der Kaninchen Polyklonal Anti-SNRPA1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SNRPA1 in Proben von Human, Maus, Ratte, Hund, Schaf, Rind (Kuh), Pferd, Meerschweinchen, Zebrafisch (Danio rerio) und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für SNRPA1 Antikörper (Middle Region) (ABIN2778901)

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Reaktivität: Human, Maus, Ratte, Hund, Schaf, Rind (Kuh), Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SNRPA1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: MPGQMPPAQP LSENPPNHIL FLTNLPEETN ELMLSMLFNQ FPGFKEVRLV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SNRPA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SNRPA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 282 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SNRPA1 Antikörper (ABIN2778901)

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Details zu SNRPA1

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Andere Bezeichnung: SNRPA

Hintergrund: SNRPA binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Alias Symbols: U1A, Mud1, U1-A
Protein Interaction Partner: LENG8, METTL13, RBMX, NDUFAF3, MTUS2, U2AF2, ENOX2, QKI, SNRPA1, SNRPA, SFPQ, TRIM27, RBM3, PTBP1, PCBP2, PCBP1, HNRNPK, GABPB1, CIRBP, UBC, LIN28B, LIN28A, RNF2, EZH2, SUZ12, EED, PRKDC, GIT1, WBP4, CDKN2A, SRPK2, SRPK3, C19orf43, TP63, SMAD5, IL7R, IFIT
Protein Size: 282

Molekulargewicht: 31 kDa

Gen-ID: 6626

NCBI Accession: NM_004596, NP_004587

UniProt: P09012