RPN1 Antikörper (N-Term)

Produktnummer ABIN2778826

Der Kaninchen Polyklonal Anti-RPN1-Antikörper wurde für WB validiert. Er ist geeignet, RPN1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schwein und Saccharomyces cerevisiae zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für RPN1 Antikörper (N-Term) (ABIN2778826)

Target: RPN1 (Ribophorin 1 (RPN1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RPN1 Antikörper

Bindungsspezifität: N-Term

Sequenz: TSRATSFLLA LEPELEARLA HLGVQVKGED EEENNLEVRE TKIKGKSGRF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 100%, Zebrafish: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against RPN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 607 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RPN1 Antikörper (ABIN2778826)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu RPN1

Target: RPN1 (Ribophorin 1 (RPN1))

Andere Bezeichnung: RPN1

Hintergrund: RPN1 is a type I integral membrane protein found only in the rough endoplasmic reticulum. It is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. RPN1 forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686B16177, OST1, RBPH1
Protein Interaction Partner: UBQLN1, UBC, SGTA, SUMO3, STAU1, LGR4, SUMO1, NEDD8, MDM2, ASB5, ASB11, BMI1, EED, RNF2, EGFR, ADRB2, CLN5, CLN3, AMFR, OST4, MMS19, env, UBL4A, WHSC1, VCAM1, FN1, ATF2, VCP, ESR1, ECT2, STT3B, SND1, SYNCRIP, TECR, VDAC2, SSR3, RPN2, RPSA, ILF3, SLC25A5,
Protein Size: 607

Molekulargewicht: 69 kDa

Gen-ID: 6184

NCBI Accession: NM_002950, NP_002941

UniProt: P04843