NCBP1 Antikörper (N-Term)

Produktnummer ABIN2778796

Der Kaninchen Polyklonal Anti-NCBP1-Antikörper wurde für WB validiert. Er ist geeignet, NCBP1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen und Schwein zu detektieren.

Kurzübersicht für NCBP1 Antikörper (N-Term) (ABIN2778796)

Target: NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NCBP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: SRRRHSDEND GGQPHKRRKT SDANETEDHL ESLICKVGEK SACSLESNLE

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 88%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NCBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 790 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NCBP1

Target: NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

Andere Bezeichnung: NCBP1

Hintergrund: NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP80, MGC2087, NCBP, Sto1
Protein Interaction Partner: POLDIP3, HUWE1, EIF4G1, UPF3B, EIF3B, MTOR, RPS6KB1, ALYREF, DDX39B, THOC3, THOC2, IVNS1ABP, UBC, LIN28B, LIN28A, ZNF346, SUMO1, SUZ12, EED, RNF2, BMI1, VAT1, MVP, TTC1, PPM1G, SERPINE2, NCL, NAP1L4, GFPT1, GARS, PUS1, TARDBP, YWHAE, RUVBL1, MPG, FN1, C17
Protein Size: 790

Molekulargewicht: 92 kDa

Gen-ID: 4686

NCBI Accession: NM_002486, NP_002477

UniProt: Q09161

Pathways: Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process