CDC5L Antikörper (Middle Region)

Produktnummer ABIN2778760

Dieses Anti-CDC5L-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDC5L in WB und IHC. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Kaninchen, Pferd, Hund, Meerschweinchen, Ziege, Rind (Kuh) und Saccharomyces cerevisiae.

Kurzübersicht für CDC5L Antikörper (Middle Region) (ABIN2778760)

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Kaninchen, Pferd, Hund, Meerschweinchen, Ziege, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CDC5L Antikörper

Bindungsspezifität: Middle Region

Sequenz: LHWYTGEGMD EMEFTEAESN MNDLVSEYQQ YQDATADEQG EFEEEEGEDE

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC5L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC5L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 802 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC5L

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Andere Bezeichnung: CDC5L

Hintergrund: CDC5L shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. CDC5L has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CEF1, KIAA0432, PCDC5RP, dJ319D22.1, hCDC5, CDC5, CDC5-LIKE
Protein Interaction Partner: GOLGA2, FUS, GOLGA8F, GOLGA8EP, STAU1, UBC, LIN28A, RPA3, RPA2, RPA1, ERG, WWOX, TCP1, EED, rev, TARDBP, CSNK2A2, EMID1, CDT1, MCM10, BCAS2, GRB14, CDKN2A, CDKN1A, WHSC1, SMARCD1, ORC5, ORC2, ORC1, MCM5, MCM4, MCM3, LMO2, KRT18, EIF4A3, MAGOH, PAXIP1, MDC
Protein Size: 802

Molekulargewicht: 92 kDa

Gen-ID: 988

NCBI Accession: NM_001253, NP_001244

UniProt: Q99459

Pathways: Activation of Innate immune Response, Chromatin Binding