PRMT7 Antikörper (C-Term)

Produktnummer ABIN2778660

Der Kaninchen Polyklonal Anti-PRMT7-Antikörper wurde für WB validiert. Er ist geeignet, PRMT7 in Proben von Human, Maus, Ratte, Hund, Pferd und Meerschweinchen zu detektieren.

Kurzübersicht für PRMT7 Antikörper (C-Term) (ABIN2778660)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRMT7 Antikörper

Bindungsspezifität: C-Term

Sequenz: GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV

Homologie: Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 692 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Andere Bezeichnung: Prmt7

Hintergrund: Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Alias Symbols: 4933402B05Rik, BC006705, MGC7929
Protein Interaction Partner: Ctcfl,
Protein Size: 692

Molekulargewicht: 78 kDa

Gen-ID: 214572

NCBI Accession: NM_145404, NP_663379

UniProt: Q922X9

Pathways: Ribonucleoprotein Complex Subunit Organization