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HIF3A Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HIF3A in WB und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2778530

Kurzübersicht für HIF3A Antikörper (C-Term) (ABIN2778530)

Target

Alle HIF3A Antikörper anzeigen
HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reaktivität

  • 24
  • 10
  • 7
  • 1
Human

Wirt

  • 21
  • 4
  • 1
Kaninchen

Klonalität

  • 25
  • 1
Polyklonal

Konjugat

  • 22
  • 2
  • 1
  • 1
Dieser HIF3A Antikörper ist unkonjugiert

Applikation

  • 20
  • 13
  • 10
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    PGSLQDPSTP LLNLNEPLGL GPSLLSPYSD EDTTQPGGPF QPRAGSAQAD

    Homologie

    Human: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against HIF3A. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human HIF3A
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 667 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target

    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

    Andere Bezeichnung

    HIF3A

    Hintergrund

    HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17
    Protein Interaction Partner: HSP90AA1, VHL, EGLN3, EGLN1, EGLN2, HIF1A,
    Protein Size: 667

    Molekulargewicht

    72 kDa

    Gen-ID

    64344

    NCBI Accession

    NM_152794, NP_690007

    UniProt

    Q9Y2N7

    Pathways

    Warburg Effekt
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