SMARCB1 Antikörper (Middle Region)

Produktnummer ABIN2778302

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMARCB1 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für SMARCB1 Antikörper (Middle Region) (ABIN2778302)

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMARCB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMARCB1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PLTFVPAIAS AIRQQIESYP TDSILEDQSD QRVIIKLNIH VGNISLVDQF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SMARCB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMARCB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 376 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SMARCB1 Antikörper (ABIN2778302)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu SMARCB1

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Andere Bezeichnung: SMARCB1

Hintergrund: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144
Protein Interaction Partner: UBC, SOX2, tat, EPAS1, TRA2A, NCSTN, SAP18, EIF4A3, ARID1A, DPF1, VTN, TOP2B, SON, SMARCE1, SMARCD3, SMARCD2, SMARCD1, SMARCC2, SMARCA4, SMARCA2, SMARCC1, ARID1B, HDAC2, APP, PHF10, UBD, COPS5, CUL3, TFAP4, CAND1, RB1CC1, UBB, CEBPB, UL114, UL44, CHFR, DP
Protein Size: 376

Molekulargewicht: 41 kDa

Gen-ID: 6598

NCBI Accession: NM_001007468, NP_001007469