Fetuin A Antikörper (N-Term)

Produktnummer ABIN2778140

Dieses Anti-Fetuin A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Fetuin A in WB. Geeignet für Human, Ratte, Meerschweinchen, Hund und Pferd. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für Fetuin A Antikörper (N-Term) (ABIN2778140)

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Reaktivität: Human, Ratte, Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fetuin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Fetuin A Antikörper

Bindungsspezifität: N-Term

Sequenz: AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ NLPWGYKHTL

Homologie: Dog: 86%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AHSG. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AHSG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 367 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Fetuin A Antikörper (ABIN2778140)

Edvardsson Rasmussen, Lundström, Eriksson, Rask-Andersen, Liu, Laurell: "The Acute Effects of Furosemide on Na-K-Cl Cotransporter-1, Fetuin-A and Pigment Epithelium-Derived Factor in the Guinea Pig Cochlea." in: Frontiers in molecular neuroscience, Vol. 15, pp. 842132, (2022) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Gil-Dones, Darde, Alonso-Orgaz, Lopez-Almodovar, Mourino-Alvarez, Padial, Vivanco, Barderas: "Inside human aortic stenosis: a proteomic analysis of plasma." in: Journal of proteomics, Vol. 75, Issue 5, pp. 1639-53, (2012) (PubMed).

Details zu Fetuin A

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Andere Bezeichnung: AHSG

Hintergrund: Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: A2HS, AHS, FETUA, HSGA
Protein Interaction Partner: SUMO1, UBC, NEDD8, ATF2, ALB, VKORC1, PPP5C, FBXO2, PSMA3, GRB2, CDC42, Mad2l1, Smad3, Hsd17b7, RRAS2, INSR, DCN,
Protein Size: 367

Molekulargewicht: 39 kDa

Gen-ID: 197

NCBI Accession: NM_001622, NP_001613

UniProt: P02765