C4BPB Antikörper (N-Term)

Produktnummer ABIN2778139

Der Kaninchen Polyklonal Anti-C4BPB-Antikörper wurde für WB und IHC validiert. Er ist geeignet, C4BPB in Proben von Human, Hund und Schwein zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für C4BPB Antikörper (N-Term) (ABIN2778139)

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reaktivität: Human, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4BPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-C4BPB Antikörper

Bindungsspezifität: N-Term

Sequenz: CCLMVAWRVS ASDAEHCPEL PPVDNSIFVA KEVEGQILGT YVCIKGYHLV

Homologie: Dog: 86%, Human: 100%, Pig: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against C4BPB. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 252 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-C4BPB Antikörper (ABIN2778139)

Emery, Erdman, Bowen, Newton, Winchell, Meyer, Tong, Cook, Holloway, McCaustland, Rota, Bankamp, Lowe, Ksiazek, Bellini, Anderson: "Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus." in: Emerging infectious diseases, Vol. 10, Issue 2, pp. 311-6, (2004) (PubMed).

Details zu C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Andere Bezeichnung: C4BPB

Hintergrund: C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.
Alias Symbols: C4BP
Protein Interaction Partner: UBC, PROS1,
Protein Size: 252

Molekulargewicht: 28 kDa

Gen-ID: 725

NCBI Accession: NM_000716, NP_000707

UniProt: P20851

Pathways: Komplementsystem